Monkey’s try out new male contraceptive

A potential new approach to male contraception has been reported on the BBC news. The method involves injecting a high molecular weight polymer into the vas deferens. In the small study published in Basic and Clinical Andrology the polymer, called Vasalgel, was tested in 16 …

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New approach cuts liver function tests and saves money

Testing liver function in people on statins is largely unnecessary and costly for the NHS, say researchers.
A study, published in the British Journal of General Practice, showed that testing for only one liver enzyme, alanine transaminase (ALT), rather than the full array of up to …

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Prostate cancer in the over 70s: updated guidance

Elderly patients with prostate cancer should be managed according to their individual health status and not according to age, say updated guidelines from the International Society of Geriatric Oncology (SIOG).
Physically fit elderly men with prostate cancer should be treated the same as younger, fitter patients. …

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α-blockers effective in ureteric stone expulsion

α-blockers can increase ureteric stone expulsion and shorten the length of time to expulsion, says a large meta-analysis published in the International Journal of Clinical Practice.
67 studies, randomising 6654 patients, were included in the meta-analysis. Stone expulsion rates improved with α-blockers (RR, 1.49; 95% CI …

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Shingles vaccination declining

Shingles vaccination coverage continues to decline. In September to November 2016 the routine 70-year old vaccination cohort coverage was 33.2% compared to 37.8% in November 2015, 39.8% in November 2014 and 37.9% in November 2013. The catch-up programme also showed a decline in coverage.
Shingles vaccination …

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More docetaxel better in mCRPC

More cycles of docetaxel increase overall survival (OS) in men with metastatic castration-resistant prostate cancer (mCRPC).
A post-hoc analysis of data from the MAINSAIL study that looked at docetaxel with additional lenalidomide in mCRPC found that men receiving more that 10 cycles of docetaxel lived longer …

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Work needed to fulfil PROMIS

Urgent action needs to be taken to enable men to benefit from the recent advance in prostate cancer diagnosis, according to Prostate Cancer UK (PCUK).
The charity was responding to the widely reported Prostate MRI Imaging Study (PROMIS) results showing improved diagnosis of prostate cancer with …

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New ‘Man Manual’ – serious drinking

The Men’s Health Forum (MHF) have published a new ‘Man Manual’ to help men who drink too much.
According to MHF the 20 page, full colour A5 booklet, written by Jim Pollard and the Drinkaware team is full of simple, practical tips for controlling drinking and …

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Male risk factors for stroke

Androgen deprivation and erectile dysfunction increase the risk of stroke in men, according to a large systematic review and meta-analysis published in JAMA.
The pooled relative risks of ischaemic stroke were 1.19 (95% CI, 1.05–1.34) after androgen deprivation therapy (ADT) versus no ADT and 1.21 (95% …

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Green light for everolimus in renal cancer

The Cancer Drugs Fund has given the go-ahead for everolimus (Afinitor) in advanced renal cell carcinoma that has progressed during or after treatment with vascular endothelial growth factor targeted therapy. NICE had previously rejected the drug.
A key reason for the change in position was a …

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