Curtirsen and cabazitaxel combination failure

Combining curtirsen with cabazitaxel fails to improve overall survival in patients with metastatic castration-resistant prostate cancer that has progressed after docetaxel.
Custirsen is a second generation, highly specific antisense oligonucleotide that inhibits the production of clusterin, an anti-apoptotic protein that is upregulated in response to chemotherapy …

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Only HIV vaccine can halt pandemic

Only an HIV vaccine can bring a halt to the HIV/AIDs pandemic, according to a leading International HIV specialist.
Writing in JAMA, Dr Anthony Fauci from the National Institute of Allergy and Infectious Disease, Bethesda, Maryland, says that although an estimated 19.5 million of the estimated …

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CBT and cancer recurrence fear

Cognitive behaviour therapy (CBT) could help men who fear their prostate cancer returning.
The SWORD trial, published in the Journal of Clinical Oncology, randomised 88 cancer survivors (breast (41%), prostate (34%) and colorectal (25%) to CBT composed of a mixture of face-to-face and web-based consultations, or …

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ProstVac fails to deliver

It looks like the end of the road for prostate cancer vaccine treatment ProstVac. The company developing the drug has recently announced the termination of the phase III PROSPECT trial, which was assessing the drug in patients with metastatic castration-resistant prostate cancer. An independent data …

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Men, women and sex

Men are more than twice as likely as women to stay interested in sex when living with a partner, according to a study of British sexual attitudes published by the BMJ (http://bmjopen.bmj.com/content/7/9/e016942).
In total, 15% of men and 34% of women surveyed said they had lost …

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One in ten men have old hearts

One in ten men over 50 have a heart age 10 years older than their actual age, heightening their risk of a fatal heart attack or stroke, according to a study from Public Health England (PHE). The figure comes from an analysis of responses from …

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Dame Margaret Turner-Warwick (1924-2017)

The first woman president of the Royal College of Physicians and a giant of respiratory medicine, Professor Dame Margaret Turner-Warwick, has died aged 92.
During her final illness, in which she developed pneumonia in the right lung where she had once suffered tuberculosis, she was looked …

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Increase HIV testing, says NICE

NICE is recommending increased HIV testing in hospitals and GP practices in areas of high prevalence. In its recent Quality Standard (QS157), NICE proposes that hospitals test patients when admitted or when attending emergency departments. In general practice it says that patients registering or having …

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Black icons raise prostate cancer risk awareness

Over half of GPs (51%) aren’t aware of the increased risk of prostate cancer faced by black men. Even in areas with higher black populations a third are still not aware of the raised risk. One in four black men will get prostate cancer compared to …

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UK lagging in gastro surgery

The UK is lagging behind the rest of Europe in gastric surgery, according to leading surgeons speaking at an International Conference in London.
France, with a population similar to that of Britain, carries out 37 000 obesity operations a year, compared with just 5000 in the …

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