Different approach promising for HIV vaccine

Swiss Pharma innovator Mymetics Corporation has reported progress with its candidate HIV-1 vaccine, and further pre-human studies are now being funded by the Bill and Melinda Gates Foundation.
The company says its vaccine is proving successful when others have failed because it targets gp41, a protein …

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Study validates gene test for prostate cancer risk

A new study, presented at the European Society for Medical Oncology Congress in Madrid, has confirmed that the Oncotype DX test can reliably predict biochemical relapse after radical prostatectomy.
The study was carried out by the US Center for Prostate Disease Research to confirm earlier findings …

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New support programme for men with prostate cancer

The Movember Foundation (www.movember.com) has announced the roll-out of a new package of support for men with prostate cancer.
True NTH is a personalised programme to ‘help men and their families get access to life quality enhancing information, care and support including treatment information, lifestyle advice, …

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Polyunsaturates are best

Replacing dietary fats with polyunsaturated fats will reduce the risk of heart disease, say Finnish investigators (Arterioscler Thromb Vasc Biol 2014; pii: ATVBAHA.114.304082).
Using data from 20 years of follow-up, they modelled the impact of substituting different fats in the diet of 1981 men free of …

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Cherries may lower risk of gout

Drinking concentrated cherry juice causes a rapid increase in the excretion of uric acid and could offer a natural treatment for gout, say researchers from Newcastle upon Tyne (J Functional Foods 2014; doi: 10.1016/j.jff.2014.09.004).
Their study of 12 healthy individuals showed that drinking only 30ml of …

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Diabetic retinopathy linked to cognitive decline

People with type 2 diabetes who develop retinopathy are at increased risk of cognitive decline in the future, say US investigators (Diabetes Care 2014; Sep 5. pii: DC_140502).
Their analysis of the ACCORD trial, which was set up to explore ways to reduce cardiovascular risk in …

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Atrial thrombosis explains unexplained stroke?

A blood clot arising in the left atrial appendage may be one factor that contributes to development of an apparently unexplained ischaemic stroke, according to studies from Finland (PLoS ONE; 8(11):doi:10.1371/journal.pone.0079519 & 9(3): e90903).
Some 30–40% of ischaemic strokes and transient ischaemic attacks do not …

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Endo builds men’s health portfolio

The Irish/US pharmaceutical company Endo International has acquired US-based Auxilium Pharmaceuticals in a $2.6 billion deal that will strengthen its portfolio of men’s health products.
Endo Pharma currently markets testosterone injections and a gel, analgesics and oncology products. It aims to expand markets for Auxilium’s Xiaflex …

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Low-risk lifestyle could prevent 79% of heart attacks in men

If all middle-aged and older men adopted a healthy lifestyle, the incidence of myocardial infarction could be nearly 80% lower, say Swedish investigators (J Am Coll Cardiol 2014;64:1299–306). At the moment, only 1% of men do everything they can to reduce their risk.
In 1997, the …

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Bladder cancer therapy one step closer

Pembrolizumab, MSD’s new therapy for advanced bladder cancer, has shown promise in a phase 1 study and will now move forward to a phase 3 trial to determine its efficacy and safety.
Pembrolizumab is a monoclonal antibody that binds to the PD-1 receptor, removing an inhibitory …

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