Apalutamide improves overall survival

Apalutamide added to ongoing androgen deprivation therapy (ADT) significantly improves overall survival (OS) in patients with nonmetastatic castration-resistant prostate cancer (nmCRPC).
Earlier results from the SPARTAN study had showed that apalutamide could improve metastasis-free survival by two years but OS data was immature.
This follow-up paper published …

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New glands found while looking for prostate cancer

Researchers at the Netherlands Cancer Institute have discovered a new set of salivary glands while scanning for prostate cancer cells using a combination of CT scans and PSMA PET-CT.
Reporting in the journal Radiotherapy and Oncology (doi.org/10.1016/j.radonc.2020.09.034) the scientists identified the previously unseen glands behind the …

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Cochrane finds vaping better than NRT

Electronic cigarettes or vaping can increase quit rates compared to nicotine replacement therapy (NRT) according to an updated Cochrane Library review.
The review included 50 completed studies, involving 12 430 people, of which 26 were randomised controlled trials.
There was moderate‐certainty evidence that quit rates were higher …

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Family history predicts major events in ED

A family history of cardio-metabolic diseases in men with erectile dysfunction (ED) is a strong predictor of future major adverse cardiovascular events.
In this US study, researchers looked at data from 4693 men with ED attending an andrology clinic. Family history, cardiovascular health at presentation and …

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Prostate cancer risk checker success

So far this autumn 85 037 men have used the Prostate Cancer UK (PCUK) prostate cancer risk-checker and 67 199 men have been advised to talk to their GP about the risk of having the disease and the pros and cons of having a PSA …

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Movember is approaching!

November – or should we say Movember? – is approaching and the men’s health charity started over 16 years ago is gearing up for another month of frantic fundraising.
Like last year men are being asked to gain sponsorship for Growing a Mo (moustache or facial …

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Simpler eye drop taking for the squeamish

A simpler and easier way of taking eye drops is equally effective and safe as the traditional drop directly in the eye method, according to a recent study published in Optometry and Vision Science.
Some patients find it particularly hard to apply eye drops effectively due …

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Black men have genetically different prostate cancer

Black men have different genomic mutations in prostate cancer than White or Asian men and this may underlie differences in incidence and prognosis and help direct treatment more effectively, according to a new study in the New England Journal of Medicine.
To better understand prostate cancer …

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COVID-19 halves prostate cancer referrals

Referrals for urological cancers have halved during the COVID-19 pandemic, putting as many as 3500 men with higher-risk cancers at risk of being diagnosed too late to be cured, Prostate Cancer UK (PCUK) has warned.
Urgent referrals are at their lowest levels in 10 years, with …

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ACE drugs may benefit COVID-19 patients

Angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs), do not appear to adversely impact patients with COVID-19, and may in fact be beneficial according to a recent meta-analysis published in Current Atherosclerosis Reports.
Because COVID-19 enters cells via the ACE receptor concern has been raised …

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