TRoMbone calls for recruits

Researchers are recruiting patients for a pilot study looking at the potential benefits of radical prostatectomy plus extended pelvic lymphadectomy in addition to standard treatment in patients with prostate cancer and oligometastases to the bone.

There is some evidence that treating the primary tumour in men with oligometastatic prostate cancer can improve outcomes.

The UK feasibility randomised trial Testing Radical prostatectomy in men with prostate cancer and oligoMetastases to the bone (TRoMbone) is being conducted at Oxford University Hospitals, University College London Hospitals and Royal Surrey County Hospital. The investigators are looking for men under 75 with newly-diagnosed prostate cancer and 1¬–3 skeletal lesions on any standard-of-care imaging who are fit for surgery.

Investigator Prasanna Sooriakumaran, Consultant Urological Surgeon at University College Hospital, London, says: ‘We need to recruit 50 men over a 12-month period, and are seeking referrals from other centres to increase accrual. Centres that demonstrate ability to refer eligible patients will be able to take part in the main trial if we can demonstrate feasibility in this phase and get funding for the larger study.’

TRoMbone is managed by the Surgical Intervention Trials Unit at the University of Oxford and funded by the Prostate Cancer Foundation and The Urology Foundation.

Further details can be obtained from Prasanna Sooriakumaran ( or the study co-ordinator Neelam Hassanali (

Click here to access our blog on the TRoMbone trial and feel free to leave a comment. 

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